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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
19.09
Human Site:
S345
Identified Species:
28
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
S345
A
V
E
I
A
R
C
S
R
G
Q
Y
F
G
E
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
S404
A
V
E
I
A
R
C
S
R
G
Q
Y
F
G
E
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
S388
A
V
E
I
A
R
C
S
R
G
Q
Y
F
G
E
Dog
Lupus familis
XP_849179
417
46163
S344
A
V
E
I
A
R
C
S
R
G
Q
Y
F
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
F343
A
V
E
I
A
R
C
F
R
G
Q
Y
F
G
E
Rat
Rattus norvegicus
P12369
416
46104
L343
A
V
E
I
A
R
C
L
R
G
Q
Y
F
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
N263
G
E
L
A
L
V
T
N
K
P
R
A
A
S
A
Chicken
Gallus gallus
Q5ZM91
382
43332
A320
F
V
E
V
G
R
L
A
P
S
D
Y
F
G
E
Frog
Xenopus laevis
NP_001084637
402
45172
I329
A
V
E
I
A
R
Y
I
R
G
Q
Y
F
G
E
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
S327
E
V
E
I
A
R
C
S
R
G
Q
Y
F
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
E311
G
K
G
Q
Y
F
G
E
L
A
L
V
T
H
R
Honey Bee
Apis mellifera
XP_392905
383
43849
G317
V
P
A
G
G
Y
L
G
E
L
A
L
V
T
H
Nematode Worm
Caenorhab. elegans
P30625
366
41449
S306
V
V
G
H
L
G
M
S
D
Y
F
G
E
I
A
Sea Urchin
Strong. purpuratus
Q26619
369
41770
G308
E
V
A
I
Y
N
Q
G
Q
Y
F
G
E
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
S350
E
Y
G
A
V
D
V
S
K
K
G
Q
G
V
I
Red Bread Mold
Neurospora crassa
Q01386
385
42138
K321
D
S
P
V
K
N
Y
K
K
G
D
F
F
G
E
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
46.6
86.6
93.3
N.A.
0
0
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
60
86.6
93.3
N.A.
0
0
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
44
0
13
13
50
0
0
7
0
7
7
7
7
0
19
% A
% Cys:
0
0
0
0
0
0
44
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
7
0
0
7
0
13
0
0
0
0
% D
% Glu:
19
7
57
0
0
0
0
7
7
0
0
0
13
0
63
% E
% Phe:
7
0
0
0
0
7
0
7
0
0
13
7
63
0
0
% F
% Gly:
13
0
19
7
13
7
7
13
0
57
7
13
7
63
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
7
% H
% Ile:
0
0
0
57
0
0
0
7
0
0
0
0
0
7
7
% I
% Lys:
0
7
0
0
7
0
0
7
19
7
0
0
0
0
0
% K
% Leu:
0
0
7
0
13
0
13
7
7
7
7
7
0
7
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
0
0
0
0
0
7
7
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
7
0
7
0
50
7
0
0
0
% Q
% Arg:
0
0
0
0
0
57
0
0
50
0
7
0
0
0
7
% R
% Ser:
0
7
0
0
0
0
0
44
0
7
0
0
0
7
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
0
% T
% Val:
13
69
0
13
7
7
7
0
0
0
0
7
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
13
7
13
0
0
13
0
57
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _